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In addition, crocetin imparts epigenetic modulation in glioma cells through the suppression of class I histone deacetylases (HDACs)

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doi: 10.1016/j.intimp.2023.109983 98

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For instance, vitamin B6 supports GSH synthesis and restores GPX4 expression under oxidative stress, while vitamins E and K can act synergistically by directly blocking lipid peroxidation propagation (25)